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CATARANTHUS ROSEUS ISHLAB CHIQARILADIGAN VINBLASTIN MODDASINI SINTEZLASHDA ZCT GEN OILASI TA'SIRI

https://doi.org/10.5281/zenodo.15174023

Authors

  • Asatova H.S. Toshkent kimyo-texnologiya instituti Author
  • Turayev O. S. O'simliklar genetik resurslari ilmiy-tadqiqot instituti Author
  • Nurmuxamedova V.Z. Toshkent kimyo-texnologiya instituti Author

Keywords:

Cataranthus roseus, ZCT gen oilasi, Vinblastin, Vinkristin, Indol alkaloidlari, STR (Strictosidine synthase), TDC (Tryptophan decarboxylase), va D4H (Desacetoxyvindoline 4-hydroxylase)

Abstract

Cataranthus roseus (Madagaskar pervinkasi) o'simligi 
tibbiyotda qimmatbaho dori moddalarini ishlab chiqarish uchun asosiy xom ashyo 
hisoblanadi. Uning tarkibida vinblastin va vinkristin kabi monoterpenoid indol 
alkaloidlari (MIA) mavjud bo‘lib, ular saraton kasalligini davolashda ishlatiladi. 
Vinblastin – tabiatda kam uchraydigan va murakkab biosintetik jarayon orqali 
hosil qilinadigan moddadir. Ushbu jarayonda ZCT (Zinc finger Catharanthus 
transcription factor) gen oilasi muhim rol o‘ynaydi. Mazkur tezisda vinblastin 
sintezining molekulyar mexanizmlari va ZCT gen oilasining unga ta’siri tahlil 
qilinadi.

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References

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Zheng Z, Wu M (2004) Cadmium treatment enhances the production of alkaloid secondary metabolites in Catharanthus roseus. Plant Sci 166:507–514

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Published

2025-03-28 — Updated on 2025-04-08

Versions

Issue

Vol. 1 No. 1 (2025): “Biotexnologiyaning rivojlanish istiqbollari va muammolari” mavzusidagi rеspublika ilmiy anjumani

Section

SECTION 1.

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How to Cite

Asatova , H., Turayev , O. S., & Nurmuxamedova , V. (2025). CATARANTHUS ROSEUS ISHLAB CHIQARILADIGAN VINBLASTIN MODDASINI SINTEZLASHDA ZCT GEN OILASI TA’SIRI: https://doi.org/10.5281/zenodo.15174023. International Scientific and Practical Conference, 1(1), 7-8. https://bestjournalup.com/index.php/ispc/article/view/1279